TEMPE, Ariz. (AP) - No matter that it wasn't a work of art, the Arizona Cardinals got a much-needed victory, but they lost their two starting guards to what appeared to be serious ankle injuries.

Coach Bruce Arians said Friday that the team "was still in the evaluation process" of Evan Mathis and Mike Iupati.

"Mike is looking a little more promising than Evan at this moment," Arians said. "Whether or not there will be roster moves, we'll talk about it over the weekend, Steve (general manager Steve Keim) and I."

Arians praised the play of backups Earl Watford and John Wetzel, especially Wetzel, normally a tackle who hadn't played guard since training camp.

After the 33-21 win at San Francisco on Thursday night, the Cardinals are 2-3. They won't practice again until next Wednesday.

That still gives them five days of practice before a Monday night home game against the New York Jets.